Evaluating Outcomes of Immediate Breast Reconstruction (POBRAD-M)

Some women with breast cancer have their whole breast removed as part of their treatment (mastectomy). Of these women, around 31% have more surgery to create a new breast.There are two main ways to create a new breast(i)using tissue from elsewhere on the body ("autologous" reconstruction )or (ii)using a silicone implant. In recent years, it has been reported that by using a material called an "acellular dermal matrix" (ADM) the results of breast reconstruction surgery using an implant can be improved. ADMs are materials which originally come from animal or human skin. They act like a sling, supporting the lower part of an implant beneath the skin. Although ADMs have been approved for used in breast reconstruction and are safe, there is very little high quality evidence to back up their reported benefits, and some studies have suggested their use may in fact increase complications. The main purpose of this study is to find out what the actual risks and benefits of using an ADM in breast reconstruction surgery are. The investigators will follow the progress of women who have an implant based reconstruction to observe if participants develop problems; what those problems are and how participants feel about the results of their surgery. The investigators also follow the progress of women who undergo autologous reconstruction or alternative reconstructive techniques using an implant for the same reasons.

Sex

Female

Minimum age

18 Years

Inclusion Criteria:

* Informed consent given
* Unilateral or bilateral mastectomy (therapeutic, contra lateral or prophylactic)
* Immediate reconstruction;
* Suitable for immediate implant reconstruction with ADM

Exclusion Criteria:

* Patients unable to provide informed consent to participate in trial
* Patients unavailable for follow-up
* Not eligible for immediate breast reconstruction using an ADM