Clinical trial · Interventional
Neurofeedback in Decreasing Acute Radiotherapy-Induced Pain in Patients With Head and Neck Cancer
Neurofeedback for Acute Radiotherapy-Induced Pain in Head and Neck Cancer Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This pilot trial studies how well neurofeedback training works in decreasing acute radiotherapy-induced pain in patients with head and neck cancer. Neurofeedback training is a type of therapy that uses electroencephalograph and a computer software program to measure brain wave activity. Neurofeedback training may help teach patients ways to modify their own brain waves to decrease the perception of pain and improve quality of life.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Carcinoma | Head and Neck Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| LORETA Neurofeedback Training | Other | — | UNRESOLVED |
| Questionnaire Administration | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Supportive care (neurofeedback)
- description
- Beginning at weeks 4 and 5 or 5 and 6 of radiotherapy, patients undergo neurofeedback training QID TIW for up to 6 treatments. Patients also complete questionnaires over 10 minutes at baseline and after neurofeedback training.
- interventionNames
- Other: LORETA Neurofeedback Training
- Other: Questionnaire Administration
Primary outcomes (2)
- measure
- EEG
- timeFrame
- Baseline up to 1 week
- description
- The qEEG normative database is grouped by age and contains a sufficiently large sample size with means and standard deviations of the EEG time series and/or frequency domain analysis computed for each age group.
- measure
- Neurofeeback (LORETA)
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients must have the ability to understand and read English, sign a written informed consent, and be willing to follow protocol requirements * Patients must not have pain \> 2 on a scale of 0 - 10 (self report) in the head and neck before starting radiotherapy * Scheduled to undergo a 6 week course of radiotherapy for head and neck cancer * No plans to change the type of pain medication during the course of the study Exclusion Criteria: * Patients who are taking any antipsychotic medications * Patients with active central nervous system (CNS) disease, such as clinically-evident metastases or leptomeningeal disease, dementia, or encephalopathy * Patients who have ever been diagnosed with bipolar disorder or schizophrenia * Patients with known, previously diagnosed head or neck pain from other pain syndromes or chronic pain requiring analgesics * Patients with a history of seizure disorders
References
Publications (0)
Data not yet available