Clinical trial · Interventional
Effects of Dexmedetomidine on Quality of Recovery and Analgesia After Video-assisted Thoracoscopic Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Dexmedetomidine is a selective α2 adrenergic agonist that can be considered analgesics, anxiolytic,and anti-stress effect . This randomized, double-blind placebo-controlled trial of intraoperative dexmedetomidine for improvement of quality of recovery and analgesia from surgery. Patients scheduled to undergo video-assisted thoracoscopic surgery (VATS) will be enrolled. Patients will be recruited before the date of their surgery and will complete the Quality of Recovery-40 (QoR-40) questionnaire before their surgery and at 24 and 48 hours post op. They will also complete clinically significant pains score and oxygenation from the postanesthetic recovery unit (PACU).
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Video-assisted Thoracoscopic Surgery | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Dexmedetomidine | Drug | — | UNRESOLVED |
| Normal saline | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Dexmedetomidine
- interventionNames
- Drug: Dexmedetomidine
- type
- SHAM_COMPARATOR
- label
- Saline 0.9%
- interventionNames
- Drug: Normal saline
Primary outcomes (2)
- measure
- quality of recovery measured by QoR-40 questionnaire
- timeFrame
- 24 hr after operation
- measure
- pulmonary function test
- timeFrame
- 24 hr after operation
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: 1. The inclusion criteria included patients scheduled video-assisted thoracoscopic surgery for lung cancer 2. Adults above 20 years of age and providing informed consent. 3. American Society of Anesthesiologists (ASA) Physical class II, \& III patients Exclusion Criteria: 1. severe functional liver or kidney disease 2. history of chronic pain requiring opioid treatment 3. arrhythmia or received treatment with antiarrythmic drug . 4. severe bradycardia (HR \< 45 bpm) and AV block 5. pathologic esophageal lesion (esophageal stricture or varix ) 6. pregnancy 7. psychiatric/central nervous system disturbance that would preclude completion of the QoR-40 questionnaire 8. History of alcohol or drug abuse
References
Publications (0)
Data not yet available