Clinical trial · Interventional
Ultra-Violet Fluorescence Bronchial Cancer Location
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Diagnose lung cancer at an early stage is crucial for effective treatment. At these early stages, cancer is usually invisible in ambient white light when the endoscopic analysis of the bronchial mucosa. This lining is self-fluorescent at its illumination by blue light. These widely distributed autofluorescence methods detect early mucosal abnormalities. They are very sensitive but not specific to recognize the lung cancer. Thanks to European funding (EURIMUS), a new tool with fluorescent UV light has been developed. The purpose of this preliminary study is to verify the suitability for specific detection of cancerous tissue in Pneumology of this fluorescence method versus histological analysis of the tissue.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Biopsy | Other | — | UNRESOLVED |
| Rigid bronchoscopy with ultraviolet transmission | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- patients with lung cancer
- interventionNames
- Procedure: Rigid bronchoscopy with ultraviolet transmission
- Other: Biopsy
Primary outcomes (2)
- measure
- ultraviolet fluorescence ratio Iodine360 / Iodine450
- timeFrame
- Day 0
- description
- Detection of cancerous tissues and healthy or inflammatory tissues is used to calculate the sensitivity and specificity of the rigid bronchoscopy with UV transmission compared to biopsy (gold standard).
- measure
- Histology of tissue
- timeFrame
- Day 0
- description
- The histology give the final diagnosis
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient affiliated or entitled to a social security scheme * Major Patient * Patient who signed the informed consent document * Patient with a known primary cancer in bronchial level Exclusion Criteria: * Pregnant woman * Patient with a benign tumor histology * Patient with an unknown tumor histology.
References
Publications (0)
Data not yet available