Clinical trial · Observational
Work-Related Effects of Heat, Activity, and Fat in Middle Aged Men
Relationship of Occupational Heat Stress Endurance, Work, and Percentage of Body Fat in Middle Aged Men
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Obesity is associated with many undesirable health effects and disease, and middle age is associated with increased risk for disease. Unfortunately, while others have looked at the effects of obesity, gender, and middle age, the combined effects of obesity and middle age on men's ability to do work in hot industrial environments have not been satisfactorily investigated. This small study evaluates the heat tolerance of lean and obese middle aged men both while exercising and resting and the ways in which each compensate for and dissipate increasing environmental heat and heat generated by the body while exercising. As obesity is a worldwide public health crisis and as populations in many industrialized nations age, it is important to understand the combined effects of obesity and middle age for men on their ability to safely work in hot environments. Such information will permit establishing and revising of safe work standards and inform public health outreach to the target population, itself.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gender | — | UNRESOLVED | — |
| Obesity | — | UNRESOLVED | — |
| Problem of Aging | — | UNRESOLVED | — |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Body Composition Evaluation | Procedure | — | UNRESOLVED |
| Cardiopulmonary Exercise Stress Test | Procedure | — | UNRESOLVED |
| Climatic-Controlled Cardiopulmonary Exercise Stress Test | Procedure | — | UNRESOLVED |
| Pre-Exercise Risk Assessment | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Lean
- description
- Men aged 35-55 years, having \<20% body fat
- interventionNames
- Procedure: Cardiopulmonary Exercise Stress Test
- Procedure: Climatic-Controlled Cardiopulmonary Exercise Stress Test
- Procedure: Body Composition Evaluation
- Procedure: Pre-Exercise Risk Assessment
- label
- Obese
- description
- Men aged 35-55 years, having \>29% body fat
- interventionNames
- Procedure: Cardiopulmonary Exercise Stress Test
- Procedure: Climatic-Controlled Cardiopulmonary Exercise Stress Test
- Procedure: Body Composition Evaluation
- Procedure: Pre-Exercise Risk Assessment
Primary outcomes (4)
- measure
- Core (Rectal) Temperature Change with Exercise Level and Increased Heat Load
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 35 Years
- Maximum age
- 55 Years
Show eligibility criteria text
Inclusion Criteria: * Able and willing to give consent and to complete minimum study procedures, as defined by the protocol * Non-invasive resting blood pressure within normal limits * Resting electrocardiogram within normal limits * Hematology and Chemistry (blood) panels within normal limits * Urinalysis (pH, glucose, and protein) within normal limits * Negative cardiopulmonary stress test * Absence of acute or chronic metabolic, cardiovascular, pulmonary, and orthopedic disease Exclusion Criteria: * Unable or unwilling to give consent or to complete minimum study procedures, as defined by the protocol * Non-invasive resting blood pressure outside normal limits * Resting electrocardiogram outside normal limits * Hematology and Chemistry (blood) panels outside normal limits * Urinalysis (pH, glucose, and protein) outside normal limits * Positive cardiopulmonary stress test * Presence of acute or chronic metabolic, cardiovascular, pulmonary, and orthopedic disease
References
Publications (3)
- BACKGROUNDHaymes EM, McCormick RJ, Buskirk ER. Heat tolerance of exercising lean and obese prepubertal boys. J Appl Physiol. 1975 Sep;39(3):457-61. doi: 10.1152/jappl.1975.39.3.457. PMID 1176412
- BACKGROUNDKenny GP, Gagnon D, Dorman LE, Hardcastle SG, Jay O. Heat balance and cumulative heat storage during exercise performed in the heat in physically active younger and middle-aged men. Eur J Appl Physiol. 2010 May;109(1):81-92. doi: 10.1007/s00421-009-1266-4. Epub 2009 Nov 3. PMID 19885672
- BACKGROUNDDufour A, Candas V. Ageing and thermal responses during passive heat exposure: sweating and sensory aspects. Eur J Appl Physiol. 2007 May;100(1):19-26. doi: 10.1007/s00421-007-0396-9. Epub 2007 Jan 23. PMID 17242944