Clinical trial · Interventional
Laparoscopic Versus Open Liver Resection for Hepatocellular Carcinoma
A Prospective Randomized Control Trail of Laparoscopic Versus Open Liver Resection for Hepatocellular Carcinoma
NCT02526043CI-TRIAL-00060424unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of the study is to observe the curative effect and safety of laparoscopic versus open liver resection for hepatocellular carcinoma.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hepatocellular Carcinoma | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| laparoscopic hepatectomy | Procedure | — | UNRESOLVED |
| Open hepatectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- laparoscopic hepatectomy
- description
- The HCC patients who meet the Louisville consensus will be underwent the liver resection by laparoscopic surgery
- interventionNames
- Procedure: laparoscopic hepatectomy
- type
- EXPERIMENTAL
- label
- Open hepatectomy
- description
- The HCC patients who meet the Louisville consensus will be underwent the liver resection by open surgery
- interventionNames
- Procedure: Open hepatectomy
Primary outcomes (1)
- measure
- Overall survival
- timeFrame
- 5 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: 1. Diagnosis was HCC 2. The tumor was located in segment: II, III, IVb, V, VI 3. The tumor diameter \< 5cm 4. Without thrombosis in the portal vein, hepatic vein or bile duct 5. Without intrahepatic and systemic metastasis 6. The Child-pugh score was A-B7 7. The ASA（American Society of Anesthesiologists） score was I-III 8. The patient age was between 18-75 9. Sign the informed consent, and can fully understand the research content Exclusion Criteria: 1. Have surgery contraindications 2. Pregnant or lactating women 3. The Child-pugh score was B8-C 4. The ASA（American Society of Anesthesiologists） score was IV-V 5. With other malignant tumor 6. With mental illness 7. Participated in other clinical trials in the last three months 8. Underwent other treatments(chemotherapy or radiotherapy) before operation
References
Publications (13)
- BACKGROUNDIshizawa T, Gumbs AA, Kokudo N, Gayet B. Laparoscopic segmentectomy of the liver: from segment I to VIII. Ann Surg. 2012 Dec;256(6):959-64. doi: 10.1097/SLA.0b013e31825ffed3. PMID 22968066
- BACKGROUNDReich H, McGlynn F, DeCaprio J, Budin R. Laparoscopic excision of benign liver lesions. Obstet Gynecol. 1991 Nov;78(5 Pt 2):956-8. PMID 1833688
- BACKGROUNDChen KH, Jeng KS, Huang SH, Chu SH. Laparoscopic caudate hepatectomy for cancer--an innovative approach to the no-man's land. J Gastrointest Surg. 2013 Mar;17(3):522-6. doi: 10.1007/s11605-012-2115-z. Epub 2013 Jan 8. PMID 23297026
- BACKGROUNDBuell JF, Cherqui D, Geller DA, O'Rourke N, Iannitti D, Dagher I, Koffron AJ, Thomas M, Gayet B, Han HS, Wakabayashi G, Belli G, Kaneko H, Ker CG, Scatton O, Laurent A, Abdalla EK, Chaudhury P, Dutson E, Gamblin C, D'Angelica M, Nagorney D, Testa G, Labow D, Manas D, Poon RT, Nelson H, Martin R, Clary B, Pinson WC, Martinie J, Vauthey JN, Goldstein R, Roayaie S, Barlet D, Espat J, Abecassis M, Rees M, Fong Y, McMasters KM, Broelsch C, Busuttil R, Belghiti J, Strasberg S, Chari RS; World Consensus Conference on Laparoscopic Surgery. The international position on laparoscopic liver surgery: The Louisville Statement, 2008. Ann Surg. 2009 Nov;250(5):825-30. doi: 10.1097/sla.0b013e3181b3b2d8. PMID 19916210
- BACKGROUNDAfaneh C, Kluger MD. Laparoscopic liver resection: lessons at the end of the second decade. Semin Liver Dis. 2013 Aug;33(3):226-35. doi: 10.1055/s-0033-1351780. Epub 2013 Aug 13. Danish, English. PMID 23943103
- RESULTBryant R, Laurent A, Tayar C, Cherqui D. Laparoscopic liver resection-understanding its role in current practice: the Henri Mondor Hospital experience. Ann Surg. 2009 Jul;250(1):103-11. doi: 10.1097/SLA.0b013e3181ad6660. PMID 19561476
- RESULTTopal B, Fieuws S, Aerts R, Vandeweyer H, Penninckx F. Laparoscopic versus open liver resection of hepatic neoplasms: comparative analysis of short-term results. Surg Endosc. 2008 Oct;22(10):2208-13. doi: 10.1007/s00464-008-0023-9. Epub 2008 Jul 12.