Clinical trial · Interventional
Resection of the Nerve Plexus on the Right Half of Celiac and SMA Associated With Extended Pancreatoduodenectomy in the Surgical Treatment for Adenocarcinoma of the Head of Pancreas
NCT02514928CI-TRIAL-00023456unknownPhase 3ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is performed to confirm whether resection of the nerve plexus on the right half of celiac and SMA associated with extended pancreatoduodenectomy could improve survival and relieve pain of pancreatic cancer patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreatic Cancer | Malignant Pancreatic Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| resection of the nerve plexus on the right half of celiac and SMA associated with extended pancreatoduodenectomy | Procedure | — | UNRESOLVED |
| standard pancreatoduodenectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- pancreatoduodenectomy & nerve resection
- description
- Resection of the nerve plexus on the right half of celiac and SMA associated with extended pancreatoduodenectomy. Regional lymph nodes includes group 5,6,8a,8p,9,12a,12b,12c,12p,13,14a,14b,14c,16,17, according to the 2003 edition of lymph nodes group system defined by Japan Pancreas Society (JPS).
- interventionNames
- Procedure: resection of the nerve plexus on the right half of celiac and SMA associated with extended pancreatoduodenectomy
- type
- ACTIVE_COMPARATOR
- label
- pancreatoduodenectomy
- description
- Standard pancreatoduodenectomy with regional lymph nodes includes group 5,6,8a,12b,12c,13,14a,14b,17, according to the 2003 edition of lymph nodes group system defined by Japan Pancreas Society (JPS).
- interventionNames
- Procedure: standard pancreatoduodenectomy
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Signed informed content obtained prior to treatment * Age ≥ 18 years and ≤ 80 years * Eastern Cooperative Oncology Group (ECOG) performance status 0-2 * The pathological staging does not exceed the stage IIB * The expected survival after surgery ≥ 3 months * Tumor locates at the head of the pancreas without distant metastasis * No celiac trunk and superior mesenteric artery invasion by Loyer grading * No operation contraindication Exclusion Criteria: * The pathological staging exceed the stage IIB * Pancreatic cancer at the body and tail of the pancreas * Benign tumor at the head of the pancreas * Distant metastasis * Severe important organ function impairment * Active second primary malignancy or history of second primary malignancy within the last 3 years * Pregnant or nursing women * Human immunodeficiency virus (HIV)-positive patients * Patients who are unwilling or unable to comply with study procedures
References
Publications (0)
Data not yet available
No reference posted for this study.