Clinical trial · Observational
Gynaecologic Organ Segmentation and Motion Tracking Using Ultrasound
NCT02503917CI-TRIAL-00022337GENIUSunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study will establish the feasibility and accuracy of localising and outlining the uterus on ultrasound images using both healthy volunteer and cervical patient cohorts. This will enable us to determine whether or not ultrasound will be a good option to ensure the correct patient position prior to radiotherapy for cervical cancer patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cervical Cancer | Malignant Cervical Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- Healthy volunteers
- description
- Healthy female adult volunteers
- label
- Cervical cancer patients
- description
- Patients receiving radiotherapy for cervical cancer at the Royal Marsden who will receive a planning CT scan and daily CBCT scanning as part of their treatment.
Primary outcomes (2)
- measure
- Percentage of ultrasound scans with dice similarity coefficient (DSC) of >0.90 between algorithm-derived contour and ground-truth contour
- timeFrame
- DSC calculated at 24 time points for each healthy volunteer (3 days)
- description
- The DSC between the ground truth contour and the algorithm derived contour will indicate the accuracy of the segmentation algorithm.
- measure
- Coefficient of variation between of expert-drawn contours on ultrasound and expert-drawn contours on CBCT
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * healthy volunteer cohort: Healthy female adult volunteers * patient volunteer cohort: Patients receiving radiotherapy for cervical cancer who will receive a planning CT scan and daily CBCT scanning as part of their treatment. Exclusion Criteria: * both cohorts: Women who have received hysterectomies and women who are pregnant at the time of the study
References
Publications (0)
Data not yet available
No reference posted for this study.