Clinical trial · Interventional
Yield of Cryoprobe vs Flexible Forceps Pleural Biopsy
A Study to Evaluate the Yield of Pleural Biopsy With a Flexible Cryoprobe Versus Flexible Forceps During Semirigid Thoracoscopy: a Comparative Study
NCT02500277CI-TRIAL-00034671COFFEEcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a prospective study to assess the yield of pleural biopsy obtained with the routine flexible thoracoscopic biopsy forceps versus that obtained with a flexible cryoprobe during semirigid thoracoscopy
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Metastatic Malignancy | Malignant Neoplasm | CURATED_BROADER | 0.78 |
| Pleural Effusion | — | UNRESOLVED | — |
| Pleurisy | — | UNRESOLVED | — |
| Tuberculosis | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cryoprobe pleural biopsy first | Device | — | UNRESOLVED |
| Flexible forceps biopsy first | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Cryobiopsy
- description
- Pleural biopsy with a flexible cryoprobe
- interventionNames
- Device: Cryoprobe pleural biopsy first
- type
- ACTIVE_COMPARATOR
- label
- Forceps biopsy
- description
- Pleural biopsy with a flexible forceps
- interventionNames
- Device: Flexible forceps biopsy first
Primary outcomes (1)
- measure
- Yield of pleural biopsy obtained with the routine flexible thoracoscopic biopsy forceps versus that obtained with a flexible cryoprobe during semirigid thoracoscopy
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 12 Years
- Maximum age
- 79 Years
Show eligibility criteria text
Inclusion Criteria: * Age ≥12 years * Semirigid thoracoscopy being performed for diagnosis of the pleural effusion Exclusion Criteria: * Age ≥80 years * SpO2 \<88% on room air * Hemodynamic instability * Myocardial infarction or unstable angina in the last 6 wk * Lack of pleural space due to adhesions * Uncorrected coagulopathy * Failure to provide informed consent
References
Publications (0)
Data not yet available
No reference posted for this study.