We propose to examine the effects of mindfulness based stress reduction (MBSR) on outcomes of health related quality of life, disease symptoms, and biological correlates of stress in a sample of young adults with cancer. The proposed work will serve as an essential foundation for launching a program of clinical stress reduction research with this traditionally underserved population and has the potential to lead to the discovery of specific, modifiable psychosocial, behavioral, and biological mechanisms from which to address the problem of health disparities with this group.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
Group A participates in the first available MBSR course.
interventionNames
Behavioral: MBSR
type
ACTIVE_COMPARATOR
label
Group B
description
Group B waits 16 weeks before participating in the MBSR course.
interventionNames
Behavioral: MBSR
Primary outcomes (1)
measure
feasibility assessed through examination of response rate and study attrition variables
timeFrame
week 33
Eligibility
Eligibility (as posted)
Sex
All
Minimum age
18 Years
Maximum age
39 Years
Show eligibility criteria text
Inclusion Criteria:
* Must have a diagnosis of any cancer between ages 18-39
* Must have signed and dated informed consent form, which includes agreeing to study procedures
* Must be currently between 18-39 years of age
* Must be able to read, write, speak and understand English
* Must be able to perform basic activities of daily living
* Must be cognitively intact and free of serious psychiatric illness
* Must have the ability to use a touchscreen keypad on a tablet device
* Must be willing to commit to either the MBSR course or waitlist control condition
* Must be willing to commit to eHealth intervention maintenance conditions
* Must be willing to complete all assessments
Exclusion Criteria:
* Bedridden, or physical debilitation such that study participation would not be feasible or would create undue hardship
* History of diagnosed severe mental illness or hospitalization for chronic psychiatric reasons, as identified by referring physicians
* Regular user of mindfulness-based stress reduction or a similar mind-body therapy (e.g., yoga, meditation), which is defined as ≥ 3 times a week for the past 2 weeks
References
Publications (90)
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description
feasibility assessed through examination of response rate and study attrition variables
Secondary outcomes (3)
measure
effects on health related quality of life accessed through online questionnaires
timeFrame
baseline and study weeks 8, 16, 24, and 32
description
effects on health related quality of life accessed through online questionnaires
measure
the impact of eHealth maintenance support accessed through text message response
timeFrame
weekly, for the 8 consecutive weeks after the MBSR course
description
the impact of eHealth maintenance support accessed through text message response
measure
compare between-group changes in biologic measures of stress accessed through biomarkers
timeFrame
baseline and study weeks 16 and 32
description
compare between-group changes in biologic measures of stress accessed through
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