Clinical trial · Observational
Physical Functioning Throughout Lung Cancer Treatment
NCT02493114CI-TRIAL-00095140LUCATcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This trial investigates the impact of lung cancer treatment on physical status, symptoms and quality of life. Furthermore this trial investigates possible underlying causes and consequences of deconditioning.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Exercise Capacity | — | UNRESOLVED | — |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Physical Activity | — | UNRESOLVED | — |
| Quality of Life | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- Patients with lung cancer
- description
- No study intervention
- label
- Healthy controls
- description
- No study intervention
Primary outcomes (3)
- measure
- 6MWT
- timeFrame
- Before start of treatment versus 3 months after treatment initiation
- measure
- 1-minute sit to stand test
- timeFrame
- Before start of treatment versus 3 months after treatment initiation
- measure
- SPPB
- timeFrame
- Before start of treatment versus 3 months after treatment initiation
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * undergoing treatment (surgery, chemotherapy, immunotherapy, radiotherapy, and combination of the previous ones) * WHO performance status of maximal 2 Exclusion Criteria: * presence of other neoplasms in the last 2 years * bone metastasis * progressive neuromuscular and neurological diseases * unstable cardiac disease * pulmonary hypertension * interstitial lung disease * orthopedic conditions that significantly impair functional status * mental or psychiatric disorders that impair the ability to comply with study procedures. * a history of cerebrovascular accident with remaining functional consequences * a history of lung cancer * difficulties in understanding and speaking Dutch
References
Publications (1)
- DERIVEDQuadflieg K, Arents E, Haesevoets S, Van Hulle F, Hermans F, Criel M, Daenen M, Derom E, Spruit MA, Surmont V, Stevens D, Ruttens D, Demeyer H, Burtin C. Impact of cancer treatment on physical functioning, symptoms and health-related quality of life in patients with non-small cell lung cancer: A longitudinal observational study. Respir Med. 2025 Oct;247:108283. doi: 10.1016/j.rmed.2025.108283. Epub 2025 Jul 31. PMID 40752628