Clinical trial · Observational
Post-transplant Cancer Incidence and Survival in Patients With or Without Pre-transplant Cancer
NCT02491580CI-TRIAL-00018481completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Patients with previous malignancies have increasingly been accepted for renal transplantation. However, post-transplant malignancy risk and survival rates of these patients are unknown. Our aim was to assess if previous malignancies pose an unnecessarily high risk of post-transplant malignant tumours and if the organs as a resource are too limited for investment in this patient group.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Kidney Failure | — | UNRESOLVED | — |
| Neoplasms | Neoplasm | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- KTx Uppsala
- description
- Patients who have received a kidney transplant in Uppsala.
- label
- KTx Europe
- description
- Patients who have received a kidney transplant in Uppsala.
Primary outcomes (1)
- measure
- Incidence of post-transplant cancer
- timeFrame
- Up to 33 years starting in January 1982.
Secondary outcomes (2)
- measure
- Patient survival
- timeFrame
- Up to 33 years starting in January 1982.
- measure
- Cancer-induced mortality
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Kidney transplanted patients from January 1982 through December 2013 with or without a pre transplant cancer. Exclusion Criteria: * Simultaneous kidney+pancreas transplantation. * Islet cell transplanted patients * Undiagnosed malignancies at the time of transplantation * Death within a week after transplantation * First transplantation at another hospital
References
Publications (1)
- DERIVEDHellstrom V, Lorant T, Dohler B, Tufveson G, Enblad G. High Posttransplant Cancer Incidence in Renal Transplanted Patients With Pretransplant Cancer. Transplantation. 2017 Jun;101(6):1295-1302. doi: 10.1097/TP.0000000000001225. PMID 27163539