Clinical trial · Observational
the Influence of General Anesthesia on Tumor Metastasis and Recurrence
NCT02474511CI-TRIAL-00018283unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study was to investigate whether general anesthesia will affect the postoperative recurrence and metastasis of malignant tumor.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Tumor Recurrence and Metastasis | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| general anesthesia and local anesthesia | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- general anesthesia
- description
- In this group，the patient is received radiofrequency ablation under general anesthesia.
- interventionNames
- Other: general anesthesia and local anesthesia
- label
- local anesthesia
- description
- In this group，the patient is received radiofrequency ablation under local anesthesia.
- interventionNames
- Other: general anesthesia and local anesthesia
Primary outcomes (1)
- measure
- Number of participants with tumor recurrence and metastasis
- timeFrame
- 3 years
- description
- Follow-up of patients with tumor recurrence and metastasis after Radiofrequency ablation to 3 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * ASA I - III Primary liver cancer tumor is single and diameter is less than 3 centimeter There is no major vascular invasion phenomenon, no lymph nodes or extrahepatic metastases The Child - Pugh belong to type A or type B Exclusion Criteria: * Had a history of liver surgery (including radiofrequency ablation) Severe disease of heart, lung, kidney, the immune system INR \> 1.5 or platelet count is less than 45000 cells/mm3 History of opioid addiction Metastatic liver tumors Not sure of primary liver cancer Don't agree to participate in this experiment
References
Publications (1)
- DERIVEDNunez-Rodriguez E, Zhang H, Sah D, Cata JP. Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going? Adv Biol (Weinh). 2025 Oct;9(10):e00122. doi: 10.1002/adbi.202500122. Epub 2025 Aug 7. PMID 40772525