Clinical trial · Interventional
Intraoperative Acupoint Stimulation to Prevent Post-Operative Nausea and Vomiting (PONV)
Intraoperative Electrical Stimulation of the Acupoint P6 to Prevent Post-Operative Nausea and Vomiting in Women Undergoing Breast Cancer Surgery
NCT02473042CI-TRIAL-00098556completedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this clinical research study is to learn if light electrical stimulation to the wrist area during surgery is feasible in women having breast surgery.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Post-Operative Nausea and Vomiting | — | UNRESOLVED | — |
Interventions
Interventions (6)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Dexamethasone | Drug | Dexamethasone | ALIAS |
| Electrical Stimulation | Procedure | — | UNRESOLVED |
| Pepcid | Drug | — | UNRESOLVED |
| Phenergan | Drug | — | UNRESOLVED |
| Questionnaire | Behavioral | — | UNRESOLVED |
| Zofran | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Electrical Stimulation + Standard of Care Antiemetics
- description
- Participants receive light electrical stimulation to the wrist area during surgery. Participants also receive standard of care drugs to reduce post-operative nausea and vomiting (PONV). Questionnaire completed about participant's pre-treatment expectations and their nausea about 15 minutes after they wake up after surgery, then every 30 minutes until they leave the clinic.
- interventionNames
- Procedure: Electrical Stimulation
- Drug: Zofran
- Drug: Dexamethasone
- Drug: Phenergan
- Drug: Pepcid
- Behavioral: Questionnaire
- type
- ACTIVE_COMPARATOR
- label
- Standard of Care Antiemetics
- description
- Participants receive standard of care drugs to reduce post-operative nausea and vomiting (PONV). Questionnaire completed about participant's pre-treatment expectations and their nausea about 15 minutes after they wake up after surgery, then every 30 minutes until they leave the clinic.
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Adults at least 18 years of age 2. Female gender 3. History of patient reported PONV, CINV or motion sickness 4. Patients scheduled for Breast Surgery 5. Sign an informed consent indicating they are aware of the investigational nature of this study. Exclusion Criteria: 1. Patients scheduled for paravertebral block 2. Upper extremity deformity contralateral to the site of disease that could interfere with accurate point location or alter the energy pathway as defined by traditional acupuncture theory 3. Local skin infections at or near the acustimulation site 4. Pre-existing nausea and vomiting, defined as nausea or vomiting requiring pharmacological treatment greater than 3 times in the week preceding screening 5. History of CVA or other central nervous system disorder resulting in residual weakness or paresis of extremity contralateral to the site of disease 6. Grade III or IV upper extremity peripheral neuropathy 7. Cardiac pacemakers. Patients involved in this protocol will receive electrical stimulation. For safety reasons, electrical stimulation should be avoided in patients with pacemakers 8. Metal implants for the treatment extremity. For safety reasons, use of electrical stimulation should be avoided 9. Current acknowledged use of any illicit drugs, medical marijuana (including Marinol), or evidence of alcohol abuse as defined by The American Psychiatric Association criteria. This includes patients who are currently in the recovery process. 10. Pregnancy as this would alter anesthesia plan 11. Bowel obstruction 12. Surgery that would not allow access to at least one P6 site.
References
Publications (0)
Data not yet available
No reference posted for this study.