Clinical trial · Interventional
The Effect and Mechanism of Electroacupuncture on Acute Chemotherapy-induced Nausea and Vomiting
NCT02469493CI-TRIAL-00018326unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to compare the preventive effect of electroacupuncture and sham acupuncture on acute chemotherapy-induced nausea and vomiting and then investigate its potential mechanism by using functional Magnetic Resonance Imaging (fMRI).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Neoplasms | Lung Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| acupuncture (Huatuo) | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- EXPERIMENTAL
- label
- Acupuncture 1
- description
- In this group, patients separately received twice electroacupuncture at bilateral PC6 acupoint before and after Cisplatin administration on the first day of chemotherapy.
- interventionNames
- Device: acupuncture (Huatuo)
- type
- EXPERIMENTAL
- label
- Acupuncture 2
- description
- In this group, patients separately received twice electroacupuncture at bilateral PC6 and RN12 acupoints before and after Cisplatin administration on the first day of chemotherapy.
- interventionNames
- Device: acupuncture (Huatuo)
- type
- SHAM_COMPARATOR
- label
- Sham acupuncture
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * First diagnosed stage Ⅲ-Ⅳ lung cancer patients on cisplatin chemotherapy; * Right-handed and aged 18 to 75 years; * Karnosky performance status (KPS) ≥ 70; * Life expectancy ≥ 6 months. Exclusion Criteria: * Had brain metastases or other concurrent life-threatening diseases; * Nausea and/or vomiting were present 24h before chemotherapy treatment; * Suffered from or had a history of gastrointestinal diseases; * Had a history of head trauma, serious neurological or psychiatric disorders; * Participating in other clinical trials currently; * Had any contraindication to exposure to a high magnetic field or receive acupuncture
References
Publications (0)
Data not yet available
No reference posted for this study.