Multiple-portal VATS Versus Uniportal VATS Lobectomy for Non-small Cell Lung Cancer

Inclusion Criteria:

* Patients with clinical diagnosis of primary lung cancer with the age between 35 and 75 years old;
* Patients with Tumor size ≤5cm，clinically staged T1-2N0-1M0，prepared for lobectomy and mediastinal lymph node dissection;
* Patients with an American Society of Anesthesiology score of 0-1.

Exclusion Criteria:

* Patients with N2 or N3 positive or distant metastasis.
* Patients who had undergone Neoadjuvant chemotherapy.
* Patients with tumor invasion to the peripheral structures.
* Patients with previous history of thoracic operations.
* Patients with serious thoracic adhesion.
* Patients who will undergo Pneumonectomy, sleeve lobectomy, segmentectomy, wedge resection.
* Patients with preexisting chronic obstructive pulmonarydisease, asthma, or interstitial lung disease;
* Patients with cardiac, hepatic, or renal dysfunction;