Clinical trial · Interventional
Effect of Morphine, Tramadol, and Ketorolac on Postoperative Stress and Immune Responses
Comparison Between the Effects of Intravenous Morphine, Tramadol and Ketorolac on Stress and Immune Responses in Patients Undergoing Modified Radical Mastectomy
NCT02449954CI-TRIAL-00017991unknownPhase 2 / Phase 3ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Comparison between the effects of intravenous morphine, tramadol and ketorolac on stress and immune responses in patients undergoing modified radical mastectomy
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Intravenous ketorolac tromethamine | Drug | — | UNRESOLVED |
| Intravenous morphine sulphate | Drug | — | UNRESOLVED |
| Intravenous tramadol HCL | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- ACTIVE_COMPARATOR
- label
- morphine group
- description
- intravenous 0.1mg/kg morphine
- interventionNames
- Drug: Intravenous morphine sulphate
- type
- ACTIVE_COMPARATOR
- label
- tramadol group
- description
- intravenous 2 mg/kg tramadol
- interventionNames
- Drug: Intravenous tramadol HCL
- type
- ACTIVE_COMPARATOR
- label
- ketorolac group
- description
- intravenous30 mg ketorolac
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 20 Years
- Maximum age
- 60 Years
Show eligibility criteria text
Inclusion Criteria: * patients aged (20-60 years) * weighting (50 -75 Kg), * with American Society of Anesthesiologists (ASA) physical status I or II Exclusion Criteria: * Patients with known allergy to opioids or NSAIDS, * gastric or duodenal ulcer, on radiotherapy or chemotherapy * received blood transfusion before the surgery or preoperative NSAIDs, steroid or opioid medications 48 hours prior to operation
References
Publications (0)
Data not yet available
No reference posted for this study.