Clinical trial · Observational
Circulating Cell-free Tumor DNA in the Plasma of Patients With Gastrointestinal Stromal Tumors (GIST)
Circulating Cell-free Tumor DNA in the Plasma of Patients With Gastrointestinal Stromal Tumors (GIST): Detection and Correlation With Disease Status Assessed by Conventional Technique. Prospective Observational Study
NCT02443948CI-TRIAL-00025961unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This observational study is proposed to evaluate if the trend in the levels of cf-DNA evaluated on a sample of peripheral blood may be related to different clinical behaviors of the disease monitored by radiological investigations conducted.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastrointestinal Stromal Tumor (GIST) | Gastrointestinal Stromal Tumor | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Vena puncture for blood collection | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- adjuvant/follow up setting
- interventionNames
- Other: Vena puncture for blood collection
- label
- neo-adjuvant setting
- interventionNames
- Other: Vena puncture for blood collection
- label
- advanced disease
- interventionNames
- Other: Vena puncture for blood collection
Primary outcomes (1)
- measure
- Correlation of change in cf-DNA levels with disease status in GIST patients harboring specific DNA mutations
- timeFrame
- baseline, every 12 weeks, up to 2 years
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
* Male or female patients aged \>= 18 years * Histologically confirmed diagnosis of GIST of any anatomical location either by biopsy or surgical specimen * Available archival tumor tissue * Signed informed consent form Exclusion Criteria: * Impossibility to ensure adequate clinical and serum sample follow-up * Serious psychiatric disease that precludes informed consent or limits compliance
References
Publications (0)
Data not yet available
No reference posted for this study.