Clinical trial · Interventional
WEI NASAL JET for The Sedation of Outpatient Upper Gastrointestinal Endoscopy
Safety and Efficacy Evaluation of The Nasopharyngeal Airway Embedded With Jet Ventilation Catheter(WEI NASAL JET) Applied for The Sedation of Outpatient Upper Gastrointestinal Endoscopy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Low pulse oximetry is the most common adverse events during sedation for upper gastrointestinal endoscopy. The main reason is the glossoptosis after sedation. In present study a new designed nasopharyngeal airway embedded with jet ventilation catheter(WEI NASAL JET) will be utilized in order to reduce the hypoxia. At the same time the safety will be evaluated.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophagus Cancer | — | UNRESOLVED | — |
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
| Hypoxia | — | UNRESOLVED | — |
| Oesophagitis | — | UNRESOLVED | — |
| Peptic Ulcer | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Nasopharyngeal airway without jet ventilator | Device | — | UNRESOLVED |
| WEI NASAL JET | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- NO_INTERVENTION
- label
- Control group
- description
- Oxygen(2L/min) supplied with nasal catheter
- type
- EXPERIMENTAL
- label
- Nasopharyngeal airway group
- description
- Oxygen(2L/min) supplied directly through WEI NASAL JET without jet ventilator
- interventionNames
- Device: Nasopharyngeal airway without jet ventilator
- type
- EXPERIMENTAL
- label
- WEI NASAL JET group
- description
- Oxygen supplied through WEI NASAL JET with a manual jet ventilator
- interventionNames
- Device: WEI NASAL JET
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * patients undergoing upper gastrointestinal endoscopy * age over 18 years old * Signed informed consent form Exclusion Criteria: * a blood coagulation dysfunction or have a tendency of nose bleeding * a clear diagnosis of heart disease (heart failure, angina, myocardial infarction, arrhythmia, etc.) * a clear diagnosis of lung disease (asthma, chronic obstructive pulmonary disease, pulmonary embolism, pulmonary edema, lung cancer) * pregnant * liver disease * kidney disease * increase in intracranial pressure * emergency operation * multiple trauma * American Society of Anesthesiologists (ASA) Physical Status classification above IV * with mouth, nose and throat infection
References
Publications (1)
- DERIVEDQin Y, Li LZ, Zhang XQ, Wei Y, Wang YL, Wei HF, Wang XR, Yu WF, Su DS. Supraglottic jet oxygenation and ventilation enhances oxygenation during upper gastrointestinal endoscopy in patients sedated with propofol: a randomized multicentre clinical trial. Br J Anaesth. 2017 Jul 1;119(1):158-166. doi: 10.1093/bja/aex091. PMID 28974061