Clinical trial · Interventional
4D FDG PET in Esophageal Cancer
4D PET-CT Imaging in Esophageal Cancer
NCT02424864CI-TRIAL-00029709completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
FDG PET-CT image acquisition in the abdominal and thoracic region is influenced by organ motion. Respiratory movement blurs the metabolic signal of the esophageal tumor and lymph nodes. The investigators hypothesize that the metabolic signal obtained with motion compensation results in higher SUV-max values and clearer demarcation of the esophageal tumor and lymph nodes.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophageal Cancer | Malignant Esophageal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 4d PET-CT | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- 4D PET-CT
- description
- Other intervention: 4D PET-CT
- interventionNames
- Other: 4d PET-CT
Primary outcomes (1)
- measure
- The estimation of tumor size of the primary esophageal tumor on 4Dvs 3D FDG PET
- timeFrame
- one year
Secondary outcomes (1)
- measure
- Measurement of SUV max, SUV mean, and SUV peak in 4D versus 3D images of esophageal cancer and lymph nodes and number of suspected involved lymph nodes
- timeFrame
- one year
- description
- measurement of the SUV is a composite measurement in each FDG PET scan
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with pathology proven esophageal cancer or tumor highly suspicious for esophageal cancer * \> 18 years * Written informed consent Exclusion Criteria: * \<18 years * Possibility of pregnancy
References
Publications (1)
- DERIVEDVoncken FEM, Vegt E, van Sandick JW, van Dieren JM, Grootscholten C, Bartels-Rutten A, Takken SL, Sonke JJ, van de Kamer JB, Aleman BMP. Motion-compensated FDG PET/CT for oesophageal cancer. Strahlenther Onkol. 2021 Sep;197(9):791-801. doi: 10.1007/s00066-021-01761-w. Epub 2021 Apr 7. PMID 33825916