Clinical trial · Interventional
Functional Imaging and Reading Deficit in Children With NF1
Functional Magnetic Resonance Imaging and Reading Deficit in Children With NF1 Children
NCT02422732CI-TRIAL-00018888completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A monocenter pilot study on the acceptability and feasibility of a functional MRI protocol in children with NF1 with or without reading disabilities.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Neurofibromatosis Type 1 | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| genetic analysis | Genetic | — | UNRESOLVED |
| morphological and functional MRI (fMRI) | Radiation | — | UNRESOLVED |
| Neuropsychological assessments | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- Children with reading disability
- description
- Children with NF1, with reading disability if their performances on reading assessment (Alouette Test) present a delay of at least 18 months, will have Neuropsychological assessments, morphological and functional MRI (fMRI) and genetic analysis
- interventionNames
- Other: Neuropsychological assessments
- Radiation: morphological and functional MRI (fMRI)
- Genetic: genetic analysis
- type
- OTHER
- label
- Children without reading disability
- description
- Children with NF1, without reading disability if their performances on reading assessment (Alouette Test) present a less than 18-month delay, will have Neuropsychological assessments, morphological and functional MRI (fMRI) and genetic analysis.
- interventionNames
- Other: Neuropsychological assessments
- Radiation: morphological and functional MRI (fMRI)
- Genetic: genetic analysis
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 8 Years
- Maximum age
- 12 Years
Show eligibility criteria text
Inclusion Criteria: * Age included between 8 and 12 years * Child presenting a type 1 neurofibromatosis according to 2 criteria in the following criteria list : * At least 6 café au lait spots * 2 or more neurofibromas or 1 plexiform neurofibroma * axillary or inguinal freckling * 1 optic nerf glioma * 2 or more Lisch nodules * 1 osseous lesion as sphenoid dysplasia or thinning of the long bone cortex with or without pseudarthrosis * 1 A first degree relative (parent, sibling, or offspring) with NF1 by the above criteria * Membership in a national insurance * Consent of the child and the parents Exclusion Criteria: * Mental retardation (QI T \< 70) * Treated or untreated epilepsy * Visual deficit (visual Acuteness \< 4/10 * Presence of a symptomatic optic glioma * Presence of a brain tumor.
References
Publications (0)
Data not yet available
No reference posted for this study.