Clinical trial · Interventional
Effectiveness of Gum Chewing on Ileus in Chinese Colorectal Patients Underwent Laparoscopic Colorectal Surgery
Effectiveness of Gum Chewing on Reduction of Postoperative Paralytic Ileus for Chinese Colorectal Cancer Patients Underwent Laparoscopic Colorectal Surgery and Enhanced Recovery Program
NCT02419586CI-TRIAL-00033388completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Gum chewing group will have less ileus and early resume of bowel motion than control group.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| bubble gum | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- bubble gum chewing and routine care
- description
- Start chewing gum on postoperative day at three times daily with no more than 30 minutes till discharged
- interventionNames
- Other: bubble gum
- type
- NO_INTERVENTION
- label
- routine care
- description
- Non interventional group will receive existing routine care as usual
Primary outcomes (1)
- measure
- Time to first flatus
- timeFrame
- from postoperative day 0 till an expected average of day 7
- description
- Time to passage of flatus after surgery was significantly shorter in the intervention group (22 vs 39 hours, p=0.007).
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with newly diagnosed colorectal cancer undergoing laparoscopic resection in in Queen Mary Hospital * At least 18 years * Speak Cantonese * Able to follow study protocol and chewing gum study Exclusion Criteria: * Cognitive disability * Requirement of epidural analgesia * Requirement of intensive care unit/ High dependency unit care postoperatively * Inability to chew * Presence of procedure other than colorectal resection * Non Chinese
References
Publications (1)
- DERIVEDShum NF, Choi HK, Mak JC, Foo DC, Li WC, Law WL. Randomized clinical trial of chewing gum after laparoscopic colorectal resection. Br J Surg. 2016 Oct;103(11):1447-52. doi: 10.1002/bjs.10277. PMID 27654648