Clinical trial · Observational
Genetic Profiling of Liver Cancer in Patients Undergoing Liver Transplantation
Circulating MicroRNA Isoforms as Biomarkers in Hepatocellular Carcinoma and Associated Liver Transplantation
NCT02412579CI-TRIAL-00059771completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to determine whether genetic markers unique to liver cancer are present and to assess usefulness as a diagnostic tool.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hepatocellular Carcinoma | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| None - Standard of Care | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Hepatocellular Carcinoma with Cirrhosis
- description
- Subjects with hepatocellular carcinoma and cirrhosis.
- interventionNames
- Other: None - Standard of Care
- label
- Cirrhosis without Hepatocellular Carcinoma
- description
- Subjects with only cirrhosis.
- interventionNames
- Other: None - Standard of Care
Primary outcomes (1)
- measure
- Using next-generation sequencing methods to detect isomiRs across different HCC cohorts at all stages undergoing liver transplantation.
- timeFrame
- One year
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with the diagnosis of HCC who are on the wait list for liver transplantation * Patients with the diagnosis of HCC who have been admitted to hospital, scheduled to undergo liver transplantation within the following 24 hours. * Age Range: 18 to 75 years old Exclusion Criteria: * Patients with metastatic HCC and patients with the diagnosis of HCC who are not on the wait list for liver transplantation. * Patients older than 75 years old and younger than 18 years old. * Patients who are unable to consent. * Pregnant patients.
References
Publications (0)
Data not yet available
No reference posted for this study.