Clinical trial · Observational
Using Serum Parathyroid Hormones and Calcium to Improve Prostate Cancer Diagnosis
NCT02397629CI-TRIAL-00057074completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a cross sectional study to examine the relationship between serum calcium and PTHrP and serum PSA in men referred for prostate biopsy at Wake Forest University.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| This study has no intervention | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Patients Undergoing Prostate Biopsy
- description
- Men referred for biopsy because of an abnormal or suspicious PSA digital rectal exam, or both.
- interventionNames
- Other: This study has no intervention
Primary outcomes (1)
- measure
- To measure the relationship of calcium and PTH levels to PSA levels in patients receiving a prostate biopsy.
- timeFrame
- Day 1
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 40 Years
Show eligibility criteria text
Inclusion Criteria: * Men age \> 40 years * Men referred for biopsy because of an abnormal or suspicious PSA digital rectal exam, or both. * Ability and willingness to sign a written, IRB-approved informed consent document Exclusion Criteria: * Men using drugs known to interfere with serum PSA or with serum PTHrP and calcium. Drugs known to interfere with PSA include 5-alpha-reductase inhibitors (Proscar). Drugs known to interfere with calcium and/or PTH include lithium and thiazide diuretics. * Patients with prior transurethral resection of the prostate (TURP) or equivalent procedure (laser incision). In these men the reduction in prostatic volume may give a biased estimate of the relationship between PSA, calcium and PTHrP. * Patients on dialysis. These are excluded because dialysis increases the percentage of free PSA in serum.
References
Publications (0)
Data not yet available
No reference posted for this study.