Clinical trial · Observational
A Longitudinal Study of Colorectal Cancer Patients With Metastatic Disease in Middle-Norway
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The main objective is to provide original research results that may change clinical practice related to metastatic colorectal cancer. The study will evaluate treatment and patient care at different stages of the disease trajectory and the use of health care for this large group of patients. It will be possible to compare the effectiveness of chemotherapy, radiotherapy and symptomatic treatment given to "real life" patients with the efficacy reported in randomised clinical trials. By using longitudinal information on imaging, biomarkers, clinical staging and place of care it will be possible to improve patient classification at various stages of the disease. Based on this, a more appropriate, individualized treatment for colorectal cancer may be recommended during the phases of the disease trajectory. Participation in this project will not influence the treatment for colorectal cancer. All patients will be treated and followed-up according to current regional and national guidelines.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Neoplasm Metastasis | — | UNRESOLVED | — |
| Neoplasms, Colorectal | Colorectal Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| cancer treatment and follow-up according to current regional and national guidelines | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- survival
- timeFrame
- 3 years or until death
- description
- Cancer-specific and overall survival according to treatment, age, sex, biological markers
Secondary outcomes (6)
- measure
- Nutritional status
- timeFrame
- 3 years or until death
- description
- reported on PG-SGA, patient version
- measure
- Patient expectations
- timeFrame
- 3 years or until death
- description
- patient expectations about effects of chemotherapy and satisfaction with treatment
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Colon or rectal cancer with synchronous metastases. * Colon or rectal cancer with metastatic relapse after curative primary treatment (for localized disease or maximum one operation for distant metastases) * Localized colon or rectal cancer that due to tumor or patient related factors are not treated with a curative intent * Written informed consent. In patients not able to consent due to cognitive impairment consent can be by proxy Exclusion Criteria: \-
References
Publications (1)
- DERIVEDHatlevoll I, Kristensen AK, Solheim TS, Elvebakken H, Salvesen O, Oldervoll LM, Wibe A, Hofsli E. Do older patients with colorectal cancer experience more deterioration in health-related quality of life than younger patients during the first year of palliative chemotherapy? A prospective real-world observational study. J Geriatr Oncol. 2024 Apr;15(3):101715. doi: 10.1016/j.jgo.2024.101715. Epub 2024 Feb 15. PMID 38359528