Clinical trial · Observational
Hepatic Vein-sparing Hepatectomy for Colorectal Liver Metastases at the Caval Confluence
Hepatic Vein-sparing Hepatectomy for Colorectal Liver Metastases at the Caval Confluence: Validation on Intention-to-treat Analysis of a IOUS-guided Approach
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Major hepatectomies are generally selected for tumors involving the hepatic vein (HV) at the caval confluence (CC). As alternative, HV reconstruction has been proposed. The present study aimed to evaluate the feasibility and safety of a HV-sparing policy guided by intraoperative ultrasonography (IOUS) in a cohort of patients having at least one colorectal liver metastasis (CLM) in contact with a HV at CC. HV section can be avoided in the large majority of cases thanking to CLMs detachment or to HV partial resection or reconstruction: this policy seems feasible, safe, reduces the need of major hepatectomies, and oncologically provides an adequate local control.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Secondary Malignant Neoplasm of Liver | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Hepatic vein-sparing hepatectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- patients having at least one CLM
- description
- Hepatic vein-sparing hepatectomy guided by intraoperative ultrasonography
- interventionNames
- Procedure: Hepatic vein-sparing hepatectomy
Primary outcomes (1)
- measure
- the safety of HV-sparing surgery in terms of operative mortality and morbidity
- timeFrame
- within 30-90 days after surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 28 Years
- Maximum age
- 79 Years
Show eligibility criteria text
Inclusion Criteria: * diagnosis of at least one CLM in contact with HV at caval confluence and HV patency at preoperative imaging * at least 6 months of follow-up after surgery Exclusion Criteria: * suspected or ascertained thrombosis or full tumoral involvement of HV at preoperative imaging * portal pedicle infiltration and/or thrombosis * unresectability at laparotomy for any extra-hepatic or intrahepatic reason not related to tumor-vessel relations
References
Publications (0)
Data not yet available