Clinical trial · Observational
Pilot Study of Coil Arrays in Patients With Advanced Solid Tumor Malignancies
A Pilot Study of Novel Magnetic Resonance Coil Arrays to Improve the Characterization of Liver Metastases in Patients With Advanced Solid Tumor Malignancies
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a single center pilot study testing the use of novel coil arrays with MR liver imaging. In part A of the study, up to 30 healthy volunteers will be scanned, with iterative adjustment of coil array geometry and design to optimize imaging characterstics. In Part B of the study, 40 patients with advanced solid tumors and at least one liver metastasis measuring \> 1.5 cm in diameter on standard anatomic scans will undergo MR liver imaging with the newly designed coil array, with the use of gadolinium contrast. Patients with liver tumors will have the option of undergoing a second MR liver scan during the course of subsequent systemic therapy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Neoplams | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MRI | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- MRI
- description
- Day 1
- interventionNames
- Procedure: MRI
Primary outcomes (3)
- measure
- Spatial Resolution
- timeFrame
- Day 1
- description
- Adjust the coil array to optimize spatial resolution in healthy volunteers
- measure
- Scan coverage
- timeFrame
- Day 1
- description
- Adjust the coil array to optimize scan coverage of the liver in healthy volunteers
- measure
- Mean contrast-to-noise ratio
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria (Part B only - Patients with advanced solid tumor): * Advanced solid tumor malignancy and the presence of at least one liver metastasis measuring \> 1.5 cm in longest diameter in axial dimension on standard anatomic imaging Exclusion Criteria (Part B only): * Contra-indication to gadolinium contrast (e.g. chronic renal disease, prior allergic reaction) for patient studies Exclusion Criteria (Part A \[Healthy Volunteers\] and Part B): * Contra-indication to MRI (e.g. pacemaker, severe claustrophobia, suspected presence of MR-Unsafe surgical implants or shrapnel)
References
Publications (0)
Data not yet available