Clinical trial · Observational
Defining PET / CT Protocols With Optimized F18-FDG (Fluorodeoxyglucose) Dose, Focusing on Reduced Radiation Dose and Improved Image Quality
NCT02378337CI-TRIAL-00030549pet-ctcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Identify the best combination of predictive variables that influence ionizing radiation dose and improved image quality through analysis and quantification of PET-CT images in simulators and patients.
Conditions
Conditions (8)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hodgkin Disease | Hodgkin Lymphoma | ALIAS | 0.90 |
| Malignant Melanoma of the Skin | — | UNRESOLVED | — |
| Malignant Neoplasm of Breast | Malignant Breast Neoplasm | ALIAS | 0.90 |
| Malignant Neoplasm of Bronchus and Lung | — | UNRESOLVED | — |
| Malignant Neoplasm of Colon | Malignant Colon Neoplasm | ALIAS | 0.90 |
| Malignant Neoplasm of Small Intestine | Malignant Small Intestinal Neoplasm | ALIAS | 0.90 |
| Non-Hodgkin Lymphoma, Follicular (Nodular) | Non-Hodgkin Lymphoma | ONTOLOGY_EXACT | 0.85 |
| Secondary Neoplasm Malignant and Unspecified Lymph Nodes | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Image quantify | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Retrospective development cohort
- description
- A total of 85 18F-FDG-PET adult studies were gathered over a 3-month period and retrospectively evaluated.
- interventionNames
- Other: Image quantify
- label
- Prospective validation cohort
- description
- To verify the application of methodology in clinical routine, we conducted a second phase of the study prospectively in 250 subjects (phase 2) using inclusion and exclusion criteria of the retrospective study (phase 1).
- interventionNames
- Other: Image quantify
Primary outcomes (1)
- measure
- Correlation of body weight with the variation coefficient (image noise).
- timeFrame
- 360 seconds
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Healthy volunteers; * Both genders; * Age over 18 years; * Clinical indication for PET-CT scan. Exclusion Criteria: * Pregnant women; * Patients who have lesions in the liver metabolically active whether primary or metastatic; * Patients with movement difficulties.
References
Publications (0)
Data not yet available
No reference posted for this study.