Clinical trial · Interventional
Paracervical Vasopressin Injection Compared With Intramyometrial Vasopressin in Abdominal Myomectomy
Paracervical Vasopressin Injection Compared With Intramyometrial Vasopressin in Abdominal Myomectomy: A Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Study never started
Summary
Brief summary (as posted)
The goal of the investigators study is to evaluate the effectiveness of paracervical injection of vasopressin at the time of abdominal myomectomy to decrease blood loss. The investigators will continue to use intramyometrial vasopressin as this has previously been shown to be effective. The study will not exceed the safely documented dose of vasopressin.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Myoma | Myoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Vasopressins | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Paracervical & Intramyometrial
- description
- Vasopressin will be placed paracervically (8mL, 4 units) and intramyometrial (8mL, 4 units)
- interventionNames
- Drug: Vasopressins
- type
- ACTIVE_COMPARATOR
- label
- Intramyometrial
- description
- Vasopressin will be placed intramyometrial (16mL, 8 units)
- interventionNames
- Drug: Vasopressins
Primary outcomes (1)
- measure
- 1. Estimating blood loss at the end of myomectomy (calculated as [total suction canister volume] +[laparotomy pads] - [volume of irritation used] - [volume of vasopressin used])
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 60 Years
Show eligibility criteria text
Inclusion Criteria: * Age 18-60 years old * All women who are candidates for abdominal myomectomy and are willing to accept randomization Exclusion Criteria: * Patients unable to consent for the study * Suspected malignancy * History of adverse reaction or allergy to vasopressin * Active cardiovascular or pulmonary disease that would indicate a contraindication to use of vasopressin
References
Publications (0)
Data not yet available