Clinical trial · Interventional
Effect of SVV Guided Fluid Therapy on Blood Loss and Postoperative Outcomes
Effect of Stroke Volume Variation Guided Fluid Therapy on the Blood Loss and Postoperative Outcomes in Radical Cystectomy
NCT02373735CI-TRIAL-00020382completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to investigate the effect of stroke volume variation (SVV) guided fluid therapy on the blood loss and postoperative outcomes in radical cystectomy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bladder Cancer | Malignant Bladder Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| colloid | Other | — | UNRESOLVED |
| crystalloid | Other | — | UNRESOLVED |
| lasix | Other | — | UNRESOLVED |
| mannitol | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Group A (SVV <10% group)
- description
- * infuse crystalloid (Hartmann's solution) 6-10 ml/kg/hr continuously during surgery * infuse colloid (Volulyte) 200 ml if SVV is ≥ 10% during the surgery Interventions: crystalloid (Hartmann's solution), colloid (Volulyte)
- interventionNames
- Other: crystalloid
- Other: colloid
- type
- EXPERIMENTAL
- label
- Group B (SVV 10-20% group)
- description
- * infuse crystalloid (Hartmann's solution) 2-4 ml/kg/hr until cystectomy, 6-10 ml/kg/hr after cystectomy * infuse colloid (Volulyte) 200 ml if SVV is \> 20% * infuse mannitol 0.5 g/kg or lasix 5 mg if SVV \< 10% Interventions: crystalloid (Hartmann's solution), colloid (Volulyte), mannitol, lasix
- interventionNames
- Other: crystalloid
- Other: colloid
- Other: mannitol
- Other: lasix
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Bladder cancer patients who received radical cystectomy * Patients with American Society of Anesthesiologists physical status scale classification 1, 2 * Patients who agree with written informed consent Exclusion Criteria: * Patients with history of arrhythmia, heart failure patients * Patients with history of renal failure patients * Patients with history of abdominal surgery * Patients who received emergency operation * Patients who do not agree with study
References
Publications (0)
Data not yet available
No reference posted for this study.