Clinical trial · Observational
Enteropathogenic Escherichia Coli (EPEC): Does it Have a Role in Colorectal Tumourigenesis?
ROLE OF E COLI IN Colorectal Tumourigenesis
NCT02373020CI-TRIAL-00017440EPECcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Despite the characterization of many aetiologic genetic changes. The specific causative factors in the development of sporadic colorectal cancer remain unclear. This study was performed to detect the possible role of Enteropathogenic Escherichia coli (EPEC) in developing colorectal carcinoma.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Carcinoma | Colorectal Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Enteropathogenic Escherichia Coli . | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| colonoscopic biopsies | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- group 1
- description
- colonoscopic biopsies from patients with colorectal cancer patients
- interventionNames
- Other: colonoscopic biopsies
- label
- (Group 2
- description
- colonoscopic biopsies from healthy controls
- interventionNames
- Other: colonoscopic biopsies
Primary outcomes (1)
- measure
- virulence genes: eaeA, bfpA and stx. PCR
- timeFrame
- 1 week
- description
- E. coli colonies isolated from the mucosa of colorectal cancers and from healthy controls were harvested and subjected to DNA extraction (QIAGEN)
Secondary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * patients with colorectal carcinoma after have been diagnosed Exclusion Criteria: * Patients with inflammatory bowel disease (IBD) or macroscopic signs of inflammation were excluded.
References
Publications (0)
Data not yet available
No reference posted for this study.