Clinical trial · Interventional
Can Text Reminders Improve Uptake of Cervical Screening?
Can Text Reminders Improve Uptake of Cervical Screening? A RCT.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Cervical cancer is the most common cancer in women under 35 years and is a major public health concern. Fortunately, the natural history of this malignancy can be beneficially improved through cytological screening. However, the success of screening programmes depends on their ability to attract the "at risk" population, as well as the analytical sensitivity and specificity of the screening test. In the UK, screening consistently falls short of the 80% national target and recent evidence shows uptake is decreasing, in part due to the introduction of HPV vaccination programmes. In the under 30s London population, average coverage only reached 50% in 2013. Given this information, the cervical screening programme is under increasing pressure to improve uptake, and need an evidence based intervention. We aim to improve the uptake of cervical screening using SMS messaging through a randomised controlled trial. The trail will evaluate both the prevalent and incident rounds of screening and within the intervention group, analyse how the content of text reminders influences their effectiveness. Specifically we will evaluate a) neutral b) messenger c) social norms d) framed gain/loss reminders. Unlike our previous trial, this SMS reminder will encourage the booking of an appointment which has never been tested, rather than simply reminding women to attend. All women being invited for cervical screening, registered at participating GPs within Hillingdon will be eligible to participate. Women will also be provided with a 2 week window during which they can opt out of the research. Given the sample sizes we predict the trial will take 9 months.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cervical Carcinoma | Cervical Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Cervical Dysplasia | Cervical Intraepithelial Neoplasia | ALIAS | 0.90 |
Interventions
Interventions (6)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Framed Gain text reminder | Other | — | UNRESOLVED |
| Framed Loss text reminder | Other | — | UNRESOLVED |
| Messenger text message reminder | Other | — | UNRESOLVED |
| Neutral text message reminder | Other | — | UNRESOLVED |
| Social Norms A reminder | Other | — | UNRESOLVED |
| Social Norms B reminder | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (9)
- type
- NO_INTERVENTION
- label
- No intervention, 24-29 years
- description
- No intervention, group 24-29 years. Women will receive the written invitation to screening only
- type
- EXPERIMENTAL
- label
- Messenger text message reminder, 24-29
- description
- Messenger text message reminder, group 24-29 years.
- interventionNames
- Other: Messenger text message reminder
- type
- NO_INTERVENTION
- label
- No intervention, 30-64 years
- description
- No intervention group 30-64 years, Women will receive the written invitation to screening only
- type
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 24 Years
- Maximum age
- 64 Years
Show eligibility criteria text
Inclusion Criteria: Women aged 24-64 years being invited for cervical screening during the course of the study. Women included in the study will be registered with a GP Practice that has agreed to participate in the trial. Exclusion Criteria: Patients who opt-out, Patients who have had a hysterectomy, Patients who have informed GP practices of preference to not be screened, Patients Cervical cancer
References
Publications (1)
- DERIVEDHuf S, Kerrison RS, King D, Chadborn T, Richmond A, Cunningham D, Friedman E, Shukla H, Tseng FM, Judah G, Darzi A, Vlaev I. Behavioral economics informed message content in text message reminders to improve cervical screening participation: Two pragmatic randomized controlled trials. Prev Med. 2020 Oct;139:106170. doi: 10.1016/j.ypmed.2020.106170. Epub 2020 Jun 29. PMID 32610059