Clinical trial · Observational
Dual Energy Computed Tomography (CT) in Finding Bone Metastases in Patients With Cancer
Evaluation of Bone Metastases With Dual Energy Computed Tomography (CT)
NCT02354326CI-TRIAL-00036945terminatedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): No bone lesions detected and poor accrual
Summary
Brief summary (as posted)
This clinical trial studies dual energy computed tomography (CT) in finding cancer that has spread from the original (primary) tumor to the bone (bone metastases) in patients with cancer. Diagnostic procedures, such as dual energy CT, may help find and diagnose bone metastases and may be more accurate compared to single energy CT alone.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Malignant Neoplasm | Malignant Neoplasm | ONTOLOGY_EXACT | 0.90 |
| Metastatic Malignant Neoplasm to the Bone | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| computed tomography | Radiation | — | UNRESOLVED |
| virtual non-calcium dual-energy computed tomography | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Diagnostic (VNC DECT)
- description
- Patients undergo CT scans. Additional images will be processed with virtual non-calcium (VNC) dual energy CT (DECT) information. Comparison will be made between images with and without addition of VNC.
- interventionNames
- Radiation: virtual non-calcium dual-energy computed tomography
- Radiation: computed tomography
Primary outcomes (4)
- measure
- Number of Lesions Present
- timeFrame
- within 30 days of first treatment
- description
- Number of lesions detected at the 46 designated locations at the time of the VNC DECT
- measure
- Number of lesions absent
- timeFrame
- within 30 days of first treatment
- description
- Number of absent lesions from the 46 designated locations at the time of the VNC DECT
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients being imaged with PET/CT for diagnosis and/or staging of disease at Case Comprehensive Cancer Center * Patients with bone metastases on PET/CT * Patients without bone metastases on PET/CT * All cancer types and both newly diagnosed and previously treated patients will be included Exclusion Criteria: * Patients with intervening treatment during the time between diagnostic CT and PET/CT * Time between the diagnostic CT and PET/CT greater than 30 days
References
Publications (0)
Data not yet available
No reference posted for this study.