Clinical trial · Interventional
Effects of Multimodal Cognitive Enhancement Therapy (MCET) for Ealy Dementia
Effects of Multimodal Cognitive Enhancement Therapy (MCET) for People With Mild Cognitive Impairment and Early Stage Dementia: a Randomized, Controlled, Double-blind, Cross-over Trial
NCT02350738CI-TRIAL-00018688completedPhase 3ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study evaluates the effects of Multimodal Cognitive Enhancement Therapy (MCET) for people with mild cognitive impairment and early stage dementia by a randomized, controlled (mock-therapy), double-blind, cross-over trial
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Dementia, Mild | — | UNRESOLVED | — |
| Mild Cognitive Impairment | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Period II MCET (8 wks) | Other | — | UNRESOLVED |
| Period I MCET (8 wks) | Other | — | UNRESOLVED |
| Washout (4 wks) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- MCET_Mock group
- description
- Period I: MCET for 8 weeks (3 sessions/ week); Washout for 4 weeks and cross-over; Period II: mock therapy for 8 weeks (3 sessions/week)
- interventionNames
- Other: Period I MCET (8 wks)
- Other: Washout (4 wks)
- type
- EXPERIMENTAL
- label
- Mock_MCET group
- description
- Period I: mock therapy for 8 weeks (3 sessions/week); Washout for 4 weeks cross-over; Period II: MCET for 8 weeks (3 sessions/ week);
- interventionNames
- Other: Washout (4 wks)
- Other: Period II MCET (8 wks)
Primary outcomes (1)
- measure
- Change in the Mini-Mental State Examination for dementia screening before and after period I and before and after period II intervention (crossover part of the study)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 55 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * Aged 55-90 * Diagnosed to dementia by the Diagnostic and Statistical Manual, fourth edition (DSM-IV) or to mild cognitive impairment by International Working Group on Mild Cognitive Impairment * Clinical Dementia Rating (CDR) of 0 or 0.5 for mild cognitive impairment, 0.5 or 1 for early dementia Exclusion Criteria: * Evidence of current delirium, confusion * Any acute neurological conditions (infectious or inflammatory disorders such as viral, fungal or syphilis) or acute medical conditions * Current major psychiatric disorder by DSM-IV such as major depressive episode or manic or psychotic episode
References
Publications (0)
Data not yet available
No reference posted for this study.