Clinical trial · Observational
Procure Tumor and Initiate Melanoma Tumor-Reactive Tumor Infiltration
NCT02339987CI-TRIAL-00037202terminatedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): original PI left institute, no plan to continue using samples
Summary
Brief summary (as posted)
Procure Tumor and Initiate Melanoma Tumor-Reactive Tumor Infiltration Lymphocytes (TIL)
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Melanoma | Melanoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (2)
- measure
- Evaluate Feasibility of conducting TIL procurement in a single-site setting
- timeFrame
- 5 years
- description
- Cell viability, viable number and TIL potency using standardized methods
- measure
- Evaluate Safety of conducting TIL procurement in a single-site setting
- timeFrame
- 5 separate TIL procedures
- description
- lab personnel training during procurement, isolation, testing tumor reactivity and cryopreservation
Secondary outcomes (1)
- measure
- To determine whether TIL Procurement, isolation, testing tumor reactivity and cryopreservation can be performed at John Wayne Cancer Institute (JWCI) and Providence Saint John's Health Center (PSJHC) and infused into patients
- timeFrame
- 5 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 15 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients must have metastatic melanoma with a resectable metastasis who are undergoing resection for palliation, therapeutic or curative purpose. 2. Patients must be \> 15 years of age and must have metastatic melanoma. 3. Patients must meet standard pre-operative requirements as determined by the surgeon to be candidates for surgery. 4. Patients must be able to understand and sign the Informed Consent document. 5. Patients must be able to complete the supplemental data form Exclusion Criteria: 1. women who are pregnant or breastfeeding 2. inability to give consent
References
Publications (0)
Data not yet available
No reference posted for this study.