DoD-NCI TRICARE Feasibility Study

Background: \- Researchers at the National Cancer Institute and the Department of Defense are trying to learn more about what causes cancer, heart disease, and other health problems. To do this, they gather data on risk factors and biological markers. They get these data from large groups of people in long-running studies. As these groups of people age, researchers must form new groups. TRICARE is a health insurance program for uniformed service members and their families. It is a major part of the Military Health System. Researchers hope to form a new study group from TRICARE members. This study will test if TRICARE members will take part in a research study. Objectives: \- To test if TRICARE members will take part in a research study. Eligibility: \- TRICARE members aged 35 74 with military primary care providers at Walter Reed National Military Medical Center. They must not have a prior diagnosis of cancer other than non-melanoma skin cancer. Design: * Participants will fill out a survey. It will ask about their risk factors for cancer and other chronic diseases. Their medical records will be reviewed. They will give a blood sample. * If a larger study is formed, then participants data will be used in the larger study. They may be asked to give more samples.

Sex

All

Minimum age

35 Years

Maximum age

74 Years

* INCLUSION CRITERIA:

Participants will be selected according to the MTF, gender, age, and race/ethnicity. Beneficiaries aged 35-74 years with military primary care providers at WRNMMC or FBCH or beneficiaries living in these catchment or service areas.

EXCLUSION CRITERIA:

Beneficiaries less than 35 years of age will be excluded because cancer incidence at these ages is low and therefore it is unlikely to be feasible from a cost/information perspective to include them. Beneficiaries 75 years of age or older will be excluded because it is unlikely they will have long-term follow-up.