Clinical trial · Interventional
Nasal Saline Irrigation After Radiation Therapy for Oropharyngeal Cancer
Nasal Saline Irrigation After Radiation Therapy for Oropharyngeal Cancer: A Pilot Study
NCT02338102CI-TRIAL-00019692completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to learn whether nasal saline irrigation is beneficial to patients undergoing radiation therapy for oropharyngeal cancer.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Epistaxis | — | UNRESOLVED | — |
| Nasal Obstruction | — | UNRESOLVED | — |
| Rhinitis, Vasomotor | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Saline mixture | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Treatment Group
- description
- Subjects in this group will perform twice daily nasal irrigations. Nasal irrigations will be performed by using premeasured salt packets mixed with distilled water in NeilMed irrigation bottles. The subject will be instructed to lean forward over the sink, place the bottle up to the nostril, and hold their breath while gently squeezing the bottle. One bottle is used to irrigate both nostrils, using half the solution on each side.
- interventionNames
- Other: Saline mixture
- type
- NO_INTERVENTION
- label
- Control Group
- description
- Subjects randomized to this arm receive no intervention.
Primary outcomes (1)
- measure
- Change in quality of life, measured using Sino-Nasal Outcome Test (SNOT-20) summary scores
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * All patients seen in the KUMC Ear, Nose and Throat clinic with oropharyngeal cancer that have undergone radiation therapy as the primary treatment Exclusion Criteria: * Patients that are at high risk for infection secondary to nasal irrigation * Patients with autoimmune disease or immune deficiency
References
Publications (0)
Data not yet available
No reference posted for this study.