Clinical trial · Interventional
KV-CBCT and Ultrasound Imaging in Guiding Radiation Therapy in Patients With Prostate, Liver, or Pancreatic Cancer
Integrated 3D X-ray and Ultrasound Guided Radiation Therapy of Soft Tissue Targets
NCT02337465CI-TRIAL-00050243completedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This clinical trial studies if kilo-voltage cone beam computed tomography (KV-CBCT) and ultrasound imaging works in guiding radiation therapy in patients with prostate, liver, or pancreatic cancer. Computer systems, such as KV-CBCT and ultrasound imaging, allow doctors to create a 3-dimensional picture of the tumor may help in planning radiation therapy and may result in more tumor cells being killed.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Adult Liver Carcinoma | Adult Liver Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Malignant Pancreatic Neoplasm | Malignant Pancreatic Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Prostate Carcinoma | Prostate Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 3-Dimensional Ultrasound-Guided Radiation Therapy | Radiation | — | UNRESOLVED |
| Cone-Beam Computed Tomography | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Diagnostic (KV-CBCT, ultrasound-guided radiation therapy)
- description
- Patients undergo 3-Dimensional Ultrasound-Guided Radiation Therapy prior to and during radiation therapy. Patients also undergo kilo-voltage Cone-Beam Computed Tomography prior to radiation therapy.
- interventionNames
- Device: Cone-Beam Computed Tomography
- Radiation: 3-Dimensional Ultrasound-Guided Radiation Therapy
Primary outcomes (3)
- measure
- Percentage of Ultrasound Images Which Are Clinically Adequate for Treatment Set-up
- timeFrame
- Up to 1 year
- description
- Percentage of ultrasound images which are clinically adequate for treatment set-up in the judgment of the treating physician
- measure
- Number of Participants Able to Have the Ultrasound Probe Attached During the Entire Treatment Course
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 19 Years
Show eligibility criteria text
Inclusion Criteria: * The patient must have either 1) cancer involving the liver by biopsy or radiographic criteria, or 2) prostate cancer by biopsy, with the intent of undergoing definitive dose radiation therapy to targets within the liver, or prostate. Patients with prostatectomy receiving post-operative radiotherapy are also eligible. * Karnofsky performance status (PS) ≥ 70 * Subjects must have the ability to understand and the willingness to sign a written informational form Exclusion Criteria: * Patients with uncontrolled inter-current illness or psychiatric illness/social situations that would limit compliance with study requirements
References
Publications (0)
Data not yet available
No reference posted for this study.