Clinical trial · Observational
Leg Function and ADL After ALT Reconstruction for Head and Neck Cancer
Does Harvesting an Anterolateral Thigh (ALT) Flap Impact Lower Extremity Function and Activities of Daily Living (ADL) in Patients Undergoing Reconstructive Surgery for Head and Neck Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Anterolateral thigh (ALT) free flap tissue transfer is a commonly used method of head and neck reconstruction after head and neck cancer removal. The procedure involves removing some muscle, skin, and tissue from the thigh, and this may affect leg function. The purpose of this study is to determine the impact of ALT on ambulation and activities of daily living (ADLs)
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Free Tissue Flaps | — | UNRESOLVED | — |
| Head and Neck Neoplasms | Head and Neck Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| surveys, evaluative tests for leg function | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Lower Extremity Functional Scale
- timeFrame
- Pre- and Postoperative - subjects will be followed until discharge, and assessed again at 1 month follow-up
- description
- The Lower Extremity Functional Scale (LEFS) is a validated self-report measure designed to assess the functional capabilities of patients with any lower extremity related musculoskeletal condition. Subjects will be assessed for a change from pre- to post-operative
Secondary outcomes (3)
- measure
- Lower Extremity Function
- timeFrame
- Pre- and Postoperative - subjects will be followed until discharge, and assessed again at 1 month follow-up
- description
- Standing on one leg and walking, specifically duration of standing on one leg in minutes and distance walked up to 100 ft. Subjects will be assessed from pre-to-postoperative to determine the decline in leg function.
- measure
- Functional Independence Measure
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Over age 18; 2. Head and neck cancer; 3. To undergo anterolateral thigh free tissue transfer for head and neck reconstruction Exclusion Criteria: 1. Inability to ambulate independently prior to surgery; 2. Inability to negotiate stairs prior to surgery; 3. Inability to follow simple commands; 4. Inability to negotiate stairs prior to surgery; 5. Previous free flap harvest from either lower extremity
References
Publications (1)
- BACKGROUNDBinkley JM, Stratford PW, Lott SA, Riddle DL. The Lower Extremity Functional Scale (LEFS): scale development, measurement properties, and clinical application. North American Orthopaedic Rehabilitation Research Network. Phys Ther. 1999 Apr;79(4):371-83. PMID 10201543