Clinical trial · Interventional
The Effect of Branched-chain Amino Acid (BCAA) on the Progression of Primary Liver Cancer
NCT02327819CI-TRIAL-00016481unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Supplementation of BCAA found to reduce the risk of developing liver cancer, but the affect of BCAA on existing liver cancer is unknown. The participants (post curative intent surgery) will be supplemented with either BCAA/non-BCAA-enriched protein supplement. The intervantion will go on for 2 years or until a new liver tumor is found.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Primary Liver Cancer | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Branched-chain amoni acids (BCAA) | Dietary Supplement | — | UNRESOLVED |
| non-BCAA protein supplement | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- BCAA supplement
- description
- Branched-chain amino acids supplement, 12 g/day
- interventionNames
- Dietary Supplement: Branched-chain amoni acids (BCAA)
- type
- SHAM_COMPARATOR
- label
- non-BCAA protein supplement
- description
- non-BCAA protein supplement
- interventionNames
- Dietary Supplement: non-BCAA protein supplement
Primary outcomes (1)
- measure
- time until a new liver tumor is found
- timeFrame
- 2 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * diagnosed primary liver cancer * viral or Nonalcoholic Steatohepatitis Cirrhosis * Cirrhosis rated Child-Pugh A * liver cancer rated Barcelona Clinic Liver Cancer (BCLC) A Exclusion Criteria: * Age (over 65) * liver condition rated Child-Pugh B/C * GI/Absorption issues * patients given a treatment before surgery
References
Publications (0)
Data not yet available
No reference posted for this study.