Clinical trial · Interventional
Comparison of Emergence and Oxygenation During One-lung Ventilation With Desflurane and Propofol Anesthesia
Comparison of Emergence and Recovery Time, and Evaluation of Oxygenation During One-lung Ventilation With Desflurane and Propofol Anesthesia in Lung Surgery- A Pilot Study
NCT02324283CI-TRIAL-00075768unknownN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Which is more adequate general anesthetic agent, desflurane or propofol, for emergence and recovery time, and perioperative oxygenation in lung resection surgery?
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| desflurane | Drug | — | UNRESOLVED |
| propofol | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Desflurane
- description
- Desflurane group: this group of patients receives desflurane as the main anesthetic agent in addition to remifentanil infusion at 0.1\~0.3 mcg/kg/min during one-lung anesthesia. Bispectral index will be maintained between 45 and 50. Arterial blood gases and pulmonary blood flow by using tansesphageal echocardiogrphy will be measured.
- interventionNames
- Drug: desflurane
- type
- ACTIVE_COMPARATOR
- label
- Propofol
- description
- Propofol group: this group of patients receives propofol as the main anesthetic agent in addition to remifentanil infusion at the rate of 0.1\~0.3 mcg./g/min during one-lung anesthesia. Bispectral index will be maintained between 45 and 50. Arterial blood gases and pulmonary blood flow by using tansesphageal echocardiogrphy will be measured.
- interventionNames
- Drug: propofol
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Patients agree to participate in the study * Patients undergoing lung cancer surgery requiring one-lung ventilation. * American Society of Anesthesiologists Physical Status Class 1 or 2 Exclusion Criteria: * Patients with any of the following will be excluded from lung cancer patients. * New York Heart Association Classification more than 2 * Respiratory dysfunction Vital Capacity or percent predicted Forced expiratory volume in one second is less than 50 % * Pulmonary hypertension with mean pulmonary arterial pressure more than 30 mmHg * Coagulation dysfunction * The administration of steroids and immunosuppressive agents within 3 months prior to surgery * Infection with active inflammation * Pneumonectomy patients * Cases of epidural anesthesia is contraindicated
References
Publications (0)
Data not yet available
No reference posted for this study.