Clinical trial · Interventional
Efficacy of EPA-enriched Supplement in Malnourished Head and Neck Cancer Patients Undergone Surgery
Efficacy of EPA-enriched Supplement Compared With Standard Formula on Body Weight Changing in Malnourished Head and Neck Cancer Patients Undergone Surgery: A Randomized Study
NCT02321631CI-TRIAL-00043775completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to study the effects of EPA-enriched supplement compared with conventional supplement in malnourished head and neck cancer patients undergone surgery. Primary outcome is perioperative weight changing.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| EPA-enriched supplement | Dietary Supplement | — | UNRESOLVED |
| standard formula supplement | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- EPA-enriched supplement
- description
- EPA-enriched supplement is given to the patients for 3 weeks (1 week prior to surgery and 2 weeks post surgery). The supplement composes of 2.2 gm of EPA and 630 kcal daily.
- interventionNames
- Dietary Supplement: EPA-enriched supplement
- type
- PLACEBO_COMPARATOR
- label
- standard formula supplement
- description
- The standard formula supplement is given to the patients for 3 weeks (1 week prior to surgery and 2 weeks post surgery). The supplement is 630 kcal daily without EPA.
- interventionNames
- Dietary Supplement: standard formula supplement
Primary outcomes (3)
- measure
- Change from baseline in Body weight at 3 weeks
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 15 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients diagnosed as Head an Neck cancer with pathological confirmation 2. Receiving surgery as a primary treatment 3. Malnutrition screening tool(MST) is 2 or more Exclusion Criteria: 1. Previously irradiated patient in the Head and Neck region 2. Previously receiving chemotherapy 3. Renal insufficiency with serum creatinine \> 2.5 mg/dL 4. Liver function abnormality with total serum bilirubin \> 3.0 mg/dL 5. Pregnancy
References
Publications (0)
Data not yet available
No reference posted for this study.