Clinical trial · Interventional
Effect of rhIL-11 in Patients With Thrombocytopenia for Childhood ALL
Effect of Treatment Using rhIL-11 in Patients With Thrombocytopenia After Chemotherapy for Childhood Acute Lymphoblastic Leukemia
NCT02314273CI-TRIAL-00016316completedPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this clinical research study is to find out if rhIL-11（Interleukin 11） may increase the platelet count in Childhood patients with acute lymphocytic leukemia (ALL) who develop low platelet counts while receiving standard CAT（cyclophosphamide+Cytosine arabinoside+mercaptopurine，7d） therapy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancytopenia Due to Chemotherapy | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| rhIL-11 | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- rhIL-11 group
- description
- patients receive rhIL-11(50 mcg/kg，subcutaneously)after standard chemotherapy，once a day for 10 days or until platelet count ≥80,000/mL
- interventionNames
- Drug: rhIL-11
- type
- NO_INTERVENTION
- label
- control group
- description
- control group
Primary outcomes (1)
- measure
- platelet infusion
- timeFrame
- 14 days
- description
- frequency of platelet infusion
Secondary outcomes (4)
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * new diagnosis of ALL * TBIL≤34umol/L，Cr≤120umol/L，a normal EF * age \<18 years Exclusion Criteria: * patients with uncontrolled infection * patients with Acute congestive heart failure or chronicity cardiorespiratory functional defect or serious cardiac arrhythmias
References
Publications (0)
Data not yet available
No reference posted for this study.