Clinical trial · Observational
Uterine Cavity Assessment and Endometrial Gene Expression in Tamoxifen Treated Breast Cancer Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this multi-center study is to assess the effects of Tamoxifen on the uterine cavity and endometrial abnormalities in young premenopausal women diagnosed with breast cancer. The research contains two parts: a clinical study and a laboratory study. * Clinical part: to evaluate the association between tamoxifen treatment and uterine abnormalities. * Laboratory part: to investigate the effect of Tamoxifen treatment on endometrial tissue, by exploring the molecular aspect of endometrial receptivity.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Endometrial Receptivity Post Tamoxifen Exposure | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- Post Tamoxifen exposure group
- description
- Breast cancer patients receiving or formerly received Tamoxifen for at least 1 year.
- label
- Control group
- description
- Breast cancer patients who did not receive endocrine treatment
Primary outcomes (1)
- measure
- Endometrial cells gene expression post Tamoxifen exposure
- timeFrame
- 2 years
Secondary outcomes (2)
- measure
- Endometrial thickness post Tamoxifen exposure
- timeFrame
- 2 Years
- measure
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 45 Years
Show eligibility criteria text
Inclusion Criteria: Breast cancer patients who are: * \< 45 years * premenopausal * Had no previous uterine operations (previous D\&C is allowed) * Currently receiving or having received Tamoxifen for at least 1 year. Exclusion Criteria: * None
References
Publications (0)
Data not yet available