Clinical trial · Interventional
ISOperistaltic Versus ANTIperistaltic Anastomosis After Laparoscopic Right Colectomy for Cancer
Randomized Clinical Trial Comparing Isoperistaltic Versus Antiperistaltic Side to Side Anastomosis After Right Laparoscopic Hemicolectomy for Cancer.
NCT02309931CI-TRIAL-00064527ISOVANTIcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study will provide a precise control compared to the two interventions (iso vs antiperistaltic anastomoses) with thorough measurements of the postoperative variables and complications to improve the evaluation of the surgical technique. It will also enable an evaluation of the quality of life after the procedures.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Primary Malignant Neoplasm of Ascending Colon | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| antiperistaltic side-to-side ileocecal anastomosis | Procedure | — | UNRESOLVED |
| isoperistaltic side-to-side ileocecal anastomosis | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Isoperistaltic anastomosis
- description
- Patients with right colon cancer who undergo a right laparoscopic hemicolectomy and a isoperistaltic side-to-side ileocecal anastomosis
- interventionNames
- Procedure: isoperistaltic side-to-side ileocecal anastomosis
- type
- ACTIVE_COMPARATOR
- label
- Antiperistaltic anastomosis
- description
- Patients with right colon cancer who undergo a right laparoscopic hemicolectomy and a antiperistaltic side-to-side ileocecal anastomosis
- interventionNames
- Procedure: antiperistaltic side-to-side ileocecal anastomosis
Primary outcomes (1)
- measure
- postoperative complications
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * The patient has given informed consent to participate * No surgery contraindications * Elective surgery * No pregnancy or nursery during the study * Older than 18 years * Complete preoperative cancer staging * Tumour characteristics: * Cecum, ascending, hepatic angle or transverse colon tumour confirmed by endoscopic biopsy * Radiologically resectable tumours * Absence of vascular, nervous or bone infiltration * T4 stages with near organ infiltration * Absence of peritoneal carcinomatosis * Absence of respiratory pathology that prevents for doing hydrogen breath test Exclusion Criteria: * Pregnancy * Intestinal bowel disease like Crohn's disease or ulcerative colitis. * Metastatic bone illness * Previous abdominal surgery with bowel resection * Malabsorption syndromes
References
Publications (2)
- DERIVEDIbanez N, Abrisqueta J, Lujan J, Hernandez Q, Rufete MD, Parrilla P. Isoperistaltic versus antiperistaltic ileocolic anastomosis. Does it really matter? Results from a randomised clinical trial (ISOVANTI). Surg Endosc. 2019 Sep;33(9):2850-2857. doi: 10.1007/s00464-018-6580-7. Epub 2018 Nov 13. PMID 30426254
- DERIVEDIbanez N, Abrisqueta J, Lujan J, Hernandez Q, Parrilla P. Isoperistaltic versus antiperistaltic side-to-side anastomosis after right laparoscopic hemicolectomy for cancer (ISOVANTI) trial: study protocol for a randomised clinical trial. Int J Colorectal Dis. 2017 Sep;32(9):1349-1356. doi: 10.1007/s00384-017-2840-6. Epub 2017 Jun 21. PMID 28634703