Clinical trial · Observational
Evaluation of Loratadine for G-CSF Induced Bone Pain in Patients With Hematologic Malignancies
Evaluation of Loratadine for Granulocyte-Colony Stimulating Factor Induced Bone Pain in Patients With Hematologic Malignancies
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this project is to assess the efficacy of loratadine in decreasing the incidence and severity of bone pain following G-CSF administration in patients with hematologic malignancies, patients undergoing mobilization of hematopoietic progenitor cells, and patients who have undergone an autologous hematopoietic cell transplant. This is a different patient population than those being assessed in current clinical trials.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Loratadine | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Treatment with Loratadine
- description
- Treatment with Loratadine
- interventionNames
- Drug: Loratadine
Primary outcomes (1)
- measure
- Incidence of bone pain following G-CSF administration
- timeFrame
- Day 1
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Receiving a G-CSF after the institution practice change * Receiving a G-CSF for one of the following indications: * Prevention/treatment of neutropenia along with treatment for leukemia or lymphoma * Mobilization of hematopoietic progenitor cells * Neutropenia prevention following autologous hematopoietic cell transplant * Took loratadine per protocol with G-CSF administration * Completed a survey Exclusion Criteria: * Taking daily antihistamines for allergies, asthma, or other indications, not including bone pain * Taking daily NSAIDs, with the exception of aspirin, for chronic conditions * Treatment for solid tumor cancers * Receiving bone modifying agents for bone pain associated with metastatic disease or other chronic conditions
References
Publications (0)
Data not yet available