Clinical trial · Interventional
Drug Exposure Feedback and Education for Nurses' Safety
Randomized Controlled Trial to Improve Oncology Nurses' Protective Equipment Use
NCT02283164CI-TRIAL-00040394DEFENScompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this research is to evaluate the efficacy of an audit and feedback intervention to improve personal protective equipment (PPE) use by nurses who handle hazardous drugs in the ambulatory oncology setting.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hazardous Material Handling | — | UNRESOLVED | — |
| Occupational Health | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Hazardous materials online education and study feedback | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Treatment
- description
- Hazardous materials online education and study feedback
- interventionNames
- Behavioral: Hazardous materials online education and study feedback
- type
- ACTIVE_COMPARATOR
- label
- Control then treatment
- description
- Hazardous materials online education and study feedback
- interventionNames
- Behavioral: Hazardous materials online education and study feedback
Primary outcomes (1)
- measure
- Usage of PPE
- timeFrame
- Baseline (Year 1) and follow-up (Year 3)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: * registered nurses * employed 16 hours or more per week in the ambulatory chemotherapy infusion area Exclusion Criteria: * Treatment with an antineoplastic agent in the past year.
References
Publications (2)
- BACKGROUNDFriese CR, Mendelsohn-Victor K, Wen B, Sun D, Sutcliffe K, Yang JJ, Ronis DL, McCullagh MC; DEFENS Study Investigators. DEFENS - Drug Exposure Feedback and Education for Nurses' Safety: study protocol for a randomized controlled trial. Trials. 2015 Apr 17;16:171. doi: 10.1186/s13063-015-0674-5. PMID 25928792
- BACKGROUNDFriese CR, Yang J, Mendelsohn-Victor K, McCullagh M. Randomized Controlled Trial of an Intervention to Improve Nurses' Hazardous Drug Handling. Oncol Nurs Forum. 2019 Mar 1;46(2):248-256. doi: 10.1188/19.ONF.248-256. PMID 30767961