Clinical trial · Observational
Metabolic Syndrome and Female Breast Cancer
Metabolic Syndrome and Female Breast Cancer: a Case-control Study in Southern Brazil
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The role among metabolic syndrome and breast cancer risk is not well understood and must be further explored. The objective of this study is to evaluate the association between metabolic syndrome and breast cancer in Southern Brazil. In this case-control study, breast cancer patients and controls without malignant disease, matched for age (±5 years) and menopausal status, were interviewed and asked to make a glucose, HDL-cholesterol and triglycerides test. Waist circumference and blood pressure were measured using standardized procedures. Metabolic Syndrome was considered by NCEP ATP III (2001) and IDF (2006) definitions. Cases and controls were compared in relation to the presence of diagnosed MetS (yes/no), number of metabolic abnormalities identified (1 to 5) for each definition, and according to each metabolic abnormality cutoff point.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Observation about the presence of metabolic syndrome | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Cases
- description
- newly diagnosed (within 6 months) breast cancer patients, before adjuvant or neoadjuvant treatment.
- interventionNames
- Other: Observation about the presence of metabolic syndrome
- label
- Controls
- description
- patients without any malignant disease, matched for age an menopausal status with cases.
- interventionNames
- Other: Observation about the presence of metabolic syndrome
Primary outcomes (1)
- measure
- Odds Ratio for Breast Cancer according to the presence of Metabolic Syndrome and its components
- timeFrame
- Participants will be evaluated only once before the first appointment with the oncologist (cases with a biopsy) and gynecologist (controls). The blood test results for Metabolic Syndrome parameters were collected in an expected average of 30 days.
Eligibility
Eligibility (as posted)
- Sex
- Female
Show eligibility criteria text
Inclusion Criteria: * For cases: having newly diagnosed breast cancer without adjuvant or neoadjuvant treatment; * For controls: having no evidence of cancer; be matched for age and menopausal status with controls Exclusion Criteria: * Women with a recidivated tumor, HIV infection, renal, heart or liver disease, hypothyroidism or hyperthyroidism, mobility or neurological limitations, chronicle use of corticosteroids, pacemakers or identified with severe edema were excluded.
References
Publications (0)
Data not yet available