Clinical trial · Observational
Registry for Treatment of Upper Urinary Tract Tumours
Registry for Treatment of Upper Urinary Tract Tumours; A Multi-Center, International Registry to Evaluate the Treatment of Upper Tract Urothelial Cancer: Incidence, Indications, Treatment Types and Outcomes.
NCT02281188CI-TRIAL-00048829unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this registry is to evaluate the incidence, indications and outcomes of patients presenting with UTUC in relation to the different treatment modalities used.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Upper Urinary Tract Tumours | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Recurrence rates for patients presenting with primary UTUC stratified for type of treatment
- timeFrame
- 10 years
- description
- Data collection will be divided into the following categories: Patient / tumour characteristics, assessment, treatment choice and intra-operative details, post-operative details and complications, and follow up. The following lists all categories and type of data to be gathered. Patient characteristics: demographics, risk factors, comorbidities and previous malignancies. Assessment: symptoms, imaging type, cytology, TNM staging. Treatment choice and intra-operative details: date, use of endoscopy, type of scopes, type of imaging enhancement, biopsies, results, neo adjuvant treatment specifications and treatment type. Intra-operative: date, duration, antibiotics, type of treatment, results. Post-operative: complications and Clavien-Dindo classification, instillation, adjuvant therapy, pathology. Follow up: date, status (e.g. alive without cancer, alive with cancer), recurrence, diagnostics performed, cystoscopy, cytology, results.
Secondary outcomes (1)
- measure
- Intra- and postoperative complications (including Clavien-Dindo classification)
- timeFrame
- 5 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 100 Years
Show eligibility criteria text
Inclusion Criteria: * Is presenting with a suspected primary UTUC (any stage) * Is scheduled for treatment of UUT tumour * Has signed informed consent Exclusion Criteria: * No specific exclusion criteria are defined.
References
Publications (8)
- DERIVEDZhao H, Liu K, Ng CF, de la Rosette J, Laguna P, Teoh JY. Oncological Outcomes of Different Managements of the Distal Ureter in Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma. Eur Urol Oncol. 2026 May 28:S2588-9311(26)00135-5. doi: 10.1016/j.euo.2026.05.008. Online ahead of print. PMID 42209313
- DERIVEDZhao H, Liu K, Crisci A, Te Slaa E, Habuchi T, Akand M, Ng CF, Laguna P, Teoh JY, de la Rosette J. Impact of smoking status at diagnosis on oncological outcomes of upper-tract urothelial carcinoma. Ther Adv Urol. 2025 Jun 28;17:17562872251352049. doi: 10.1177/17562872251352049. eCollection 2025 Jan-Dec. PMID 40584958
- DERIVEDLiu K, Leung DK, Wong CH, Ko IC, Horuz R, Gontero P, Laguna P, de la Rosette J, Teoh JY. Influence of tumour location on the survival outcomes of upper tract urothelial carcinoma treated with radical nephroureterectomy. World J Urol. 2025 May 3;43(1):261. doi: 10.1007/s00345-024-05432-0. PMID 40317391
- DERIVEDLiu K, Wong CH, Zhao H, Ng CF, Teoh JY, Laguna P, de la Rosette J. Impact of Antiaggregant and Anticoagulant Medications on Perioperative Complications in Upper Tract Urothelial Carcinoma. Eur Urol Open Sci. 2025 Mar 20;75:1-6. doi: 10.1016/j.euros.2025.02.007. eCollection 2025 May. PMID 40206439
- DERIVEDBaard J, Cormio L, Dasgupta R, Maruzzi D, Rais-Bahrami S, Serrano A, Geavlete B, Giannakopoulos S, de la Rosette J, Laguna P. Unveiling the challenges of UTUC biopsies and cytology: insights from a global real-world practice study. World J Urol. 2024 Mar 20;42(1):177. doi: 10.1007/s00345-024-04866-w. PMID 38507109
- DERIVEDBaard J, Shariat SF, Roupret M, Yoshida T, Saita A, Saltirov I, Burgos JR, Celik O, de la Rosette J, Laguna P. Adherence to guideline recommendations in the management of upper tract urothelial carcinoma: an analysis of the CROES-UTUC registry. World J Urol. 2022 Nov;40(11):2755-2763. doi: 10.1007/s00345-022-04168-z. Epub 2022 Oct 5.