Clinical trial · Interventional
Randomized Study of Preoperative Dexamethasone for Quality of Recovery in VATS Lung Resection Patients
NCT02275702CI-TRIAL-00053504APVcompletedPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The proposed study is a randomized, double-blind, placebo-controlled evaluation if a small dose of IV dexamethasone during induction anesthesia in association to pre and postoperative intercostal nerve block, improves quality of recovery of thoracoscopic lung resection patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Dexamethasone IV | Drug | Dexamethasone | ALIAS |
| Saline solution | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- PLACEBO_COMPARATOR
- label
- Group 1
- description
- saline solution IV, bolus
- interventionNames
- Drug: Saline solution
- type
- ACTIVE_COMPARATOR
- label
- Group 2
- description
- 0,1mg/kg systemic dose of dexamethasone, bolus
- interventionNames
- Drug: Dexamethasone IV
Primary outcomes (1)
- measure
- The primary outcome of this study will be postoperative quality of recovery measured by postoperative quality of recovery score 40 (QoR-40) global score.
- timeFrame
- During the hospital stay and 1 year later
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * resectable stage I and II lung cancer patients submitted to VATS * american society of anesthesiology Classification (ASA) I or II Exclusion Criteria: * chronic pain; * chronic analgesic consumption; * severe renal or liver disease; * endocrine or mental diseases; * poorly controlled diabetes; * allergy to bupivacaine; * previous thoracotomy; * systemic use of corticosteroids; * morbid obesity; * poor French comprehension precluding completion of the QoR-40 questionnaire; * patient refusal.
References
Publications (0)
Data not yet available
No reference posted for this study.